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Troponins T and I

Troponins are proteins that regulate muscle contractions. Troponins T and I are found in the heart. They normally cannot be detected with blood tests. However, they are released into the bloodstream when the heart is damaged.

There are several different troponin tests, some of which are capable of detecting very low levels of troponins. These high-sensitivity tests can be used to quickly identify a heart problem, such as a heart attack.

What is the purpose of this test? This test is usually ordered in the following cases:
  • When an acute coronary syndrome (sudden drop in blood supply to the heart) is suspected, such as a myocardial infarction (heart attack)
  • To check for heart damage (e.g., due to infection or after heart surgery)
How to prepare? In general, no preparation is needed.
Reference values*
  • Troponin I: ≤ 45 ng/L
  • Troponin T (TnT): ≤ 0.1 mcg/L
Associated tests The test is usually performed in the emergency department of a hospital along with other heart tests, such as the following:
  • Creatine kinase (CK or CPK) test
  • Electrocardiogram (ECG)
How is it done?
  • A blood sample is drawn, usually from a vein in the arm.
  • The test is usually repeated to compare troponin levels over a period of time.
How long before I get the results? Results come back quickly, usually the same day.
* These values are presented for information purposes only. As different laboratories may have different target values, the lab report usually specifies the values used for the test. It should also be noted that test results must be interpreted based on factors such as age, sex, and health condition. Values outside of this range may be considered normal for some individuals.

What does an abnormal test result mean?

High troponin values:

Elevated troponin levels indicate that the heart has been damaged, usually by a heart attack. The higher the troponin level, the greater the extent of the damage. It usually takes 2 to 3 hours for troponin levels to increase after the onset of a heart attack. High values may also be due to:

  • Other cardiac conditions such as heart failure and cardiac arrhythmia
  • Kidney damage
  • Blood clots in the lungs
  • A serious infection (e.g., septicemia)
  • Strenuous physical exertion

Low troponin values:

Low to undetectable troponin levels are a good result.

Factors that can interfere with test accuracy

Biotin taken as a dietary supplement may interfere with troponin tests. It can make your troponin levels appear lower than they really are. Inform your healthcare professional if you are taking biotin or any other dietary supplements.

What you should know before going for this test

When you go in for a blood test or any other medical exam, it's always a good idea to bring a complete list of any prescriptions, over-the-counter medications, or natural health products you're taking. Unless otherwise advised, it's best to take your medications as usual on blood test days. If in doubt, don't hesitate to talk to your healthcare professional.

© Copyright Vigilance Santé

The patient information leaflets are provided by Vigilance Santé Inc. This content is for information purposes only and does not in any manner whatsoever replace the opinion or advice of your health care professional. Always consult a health care professional before making a decision about your medication or treatment.

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