Apolipoprotein B and apolipoprotein A1

Home
Pharm/Assist
Laboratory tests
Apolipoprotein B and apolipoprotein A1

Apolipoproteins bind to lipid (fat) particles to carry them throughout the bloodstream. There are two main apolipoproteins: apo B and apo A. Apo B is the main component of LDL particles (bad cholesterol), while apo A is associated with HDL (good cholesterol).

Measuring Apo B and Apo A levels enables us to assess the risk of cardiovascular disease by examining the different forms of cholesterol carried in the blood.

What is the purpose of these tests?	To diagnose and monitor problems related to lipids (fats) in the blood To assess the risk of developing cardiovascular disease To assess the effectiveness of treatments To diagnose certain genetic diseases
Preparation	In general, you will not be asked to fast before undergoing this test. Follow any instructions you receive carefully.
Reference values	The values determining the need for pharmacological treatment, and the values to be reached when treatment is started, vary according to each individual's risk of cardiovascular disease.
Associated tests	Related tests include the following: Lipid profile: measures total cholesterol, HDL, LDL, as well as triglycerides, and hs-CRP. A lipoprotein (a) analysis could also be performed. Complete medical examination: a complete blood count, a blood glucose test, a glycated hemoglobin test and an estimated glomerular filtration rate can be added to the lipid profile.
How is it done?	Blood sample, usually taken from a vein in the arm.
How long before I get the results?	Results are usually ready in a day. It may take longer to receive your results.

What does an abnormal test result mean?

High values of Apo B:

Increased Apo B levels are one of the main risk factors for cardiovascular disease. Apo B levels can be elevated for various reasons:

Diabetes
Certain diseases affecting the kidneys
Hypothyroidism
Pregnancy

Poor diet
Smoking
Obesity
Certain medications (e.g., certain hormones)

Low values of Apo B:

In most cases, a low Apo B result is considered a good thing since higher levels are associated with the risk of cardiovascular disease. Other factors that can cause low Apo B levels include:

Hyperthyroidism
Malnutrition
Weight loss
Surgery

Low values of Apo A:

Low Apo A levels may be observed in individuals with certain illnesses (e.g., heart, kidney, or liver disease). Other reduction factors are modifiable such as smoking and uncontrolled diabetes.

What you should know before going for this test

When you go in for a blood test or any other medical exam, it's always a good idea to bring a complete list of any prescriptions, over-the-counter medications, or natural health products you're taking. Unless otherwise advised, it's best to take your medications as usual on blood test days. If in doubt, don't hesitate to talk to your healthcare professional.

© Copyright Vigilance Santé

The patient information leaflets are provided by Vigilance Santé Inc. This content is for information purposes only and does not in any manner whatsoever replace the opinion or advice of your health care professional. Always consult a health care professional before making a decision about your medication or treatment.